There are different methods of changing colors of layers, depending on what file-type and software you open the graphic file with.
For example, if the file-type of the graphic is Adobe In-Design, the steps to changing the color will be slightly different from changing the color of a Photoshop graphic (although very similar).
You can easily change colors of a graphic file in Adobe In-Design by doing the following (also shown in the screenshots below):
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Select the layer that you'd like to change the color of
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Select the Color Picker from the tools pane
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From the Color Picker popup, select the desired color from the color square and hue adjuster
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Select OK after picking a color